International Journal of Pure and Applied Sciences, Vol 3, No 2 (2009)

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Antimicrobial Susceptibility of P. aeruginosa Isolates Obtained From Hospitalized Patients In Zaria

E. D. Jatau, D. O. Toryila

Abstract


P. aeruginosa is commonly associated with nosocomial infections, and is often isolated from clinical specimens, and these infections are always difficult to treat. Ninety-nine (99) clinical isolates, identified bacteriologically, were tested against discs of commonly used antimicrobial agents for treating pseudomonal infections. A total of 74 (74.4%) isolates was found to be susceptible to ciprofloxacin in-vitro, followed by amikacin, 72 (72.2%) while piperacillin/tazobactam had the least antimicrobial activity (35.4%) against the P. aeruginosa isolates. The findings of this study have shown that P. aeruginosa is inherently resistant to many commonly used antimicrobial agents. The findings also show high multiple antimicrobial and cross antimicrobial resistances among the P. aeruginosa isolates tested.

Leading topic: Antimicrobial Susceptibility of P. aeruginosa isolates in Zaria.
Key words: Pseudomonas aeruginosa, Antimicrobials, Resistance, Sensitivity, β-lactamase.

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